货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
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KR0248 | IL-10/ IL10A, Mouse, Recombinant | 10ug |
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分子量 | 18.9 kDa |
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表观分子量 | 16 kDa |
片段与标签 | Ser19-Ser178 |
生物活性 | Measured by the dose-dependent co-stimulation with murine IL-4 of MC-9 cells.The ED50 for this effect is less than 2 ng/ ml. |
物种 | Mouse |
表达宿主 | E.coli |
产品特性
纯度 | >95% as determined by reducing SDS-PAGE. |
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内毒素 | <1.0 EU per μg as determined by LAL test. |
保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months |
产品介绍
Mouse Il10 is the prototypic member of the IL-10 Cytokine family, including IL-10, IL-19, IL-20, IL-22 (IL-TIF), IL-24 and IL-26. Many viruses encode viral members of the IL-10 family, such as Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV).Its main function is inhibiting the synthesis of a number of Cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. Although human and mouse IL-10 are 81% identical at the nucleotide and amino acid level, mouse IL-10 is species-specific and does not act on human cells. Interestingly, Human IL-10 is active on mouse cells.