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VEGFB (N-Fc), Human, Recombinant

  • 货号:KR0224
货号 产品名称 规格 库存 价格 数量 购买
KR0224 VEGFB (N-Fc), Human, Recombinant 10ug

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分子量 45.7 kDa
表观分子量 40&60 kDa
片段与标签 Pro22-Ala207
物种 Human
表达宿主 Human Cells

 

产品特性

 

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 <1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months

 

产品介绍

VEGFB, as known as VRF, is a member of the VEGF family of Growth Factors that share structural and functional similarity. By alternative splicing, two isoforms of mature VEGF-B containing 167 or 186 amino acid (aa) residues exist. VEGF-B is expressed in most tissues, especially in heart, skeletal muscle and pancreas. The two VEGF-B isoforms have identical amino-terminal cysteine-knot VEGF homology domains but the carboxyl end of VEGF-B167 differs from that of VEGF-B186 by the presence of a highly basic cysteine-rich heparin binding domain. VEGF-B167 and a proteolytically processed form of VEGF-B186 also bind neuropilin-1, a type I transmembrane Receptor for semaphorins/ collapsins, Ligands involved in neuron guidance.

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