货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
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KR0224 | VEGFB (N-Fc), Human, Recombinant | 10ug |
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分子量 | 45.7 kDa |
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表观分子量 | 40&60 kDa |
片段与标签 | Pro22-Ala207 |
物种 | Human |
表达宿主 | Human Cells |
产品特性
纯度 | >95% as determined by reducing SDS-PAGE. |
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内毒素 | <1.0 EU per µg as determined by LAL test. |
保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months |
产品介绍
VEGFB, as known as VRF, is a member of the VEGF family of Growth Factors that share structural and functional similarity. By alternative splicing, two isoforms of mature VEGF-B containing 167 or 186 amino acid (aa) residues exist. VEGF-B is expressed in most tissues, especially in heart, skeletal muscle and pancreas. The two VEGF-B isoforms have identical amino-terminal cysteine-knot VEGF homology domains but the carboxyl end of VEGF-B167 differs from that of VEGF-B186 by the presence of a highly basic cysteine-rich heparin binding domain. VEGF-B167 and a proteolytically processed form of VEGF-B186 also bind neuropilin-1, a type I transmembrane Receptor for semaphorins/ collapsins, Ligands involved in neuron guidance.