货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
---|---|---|---|---|---|---|
KR0213 | Omentin/ ITLN-1 (N-6His), Human, Recombinant | 10ug |
+
-
|
|
分子量 | 32.7 kDa |
---|---|
表观分子量 | 35 kDa |
片段与标签 | Thr19-Ser298 N-6His |
生物活性 | Testing in progress |
物种 | Human |
表达宿主 | E.coli |
产品特性
纯度 | >90% as determined by reducing SDS-PAGE. |
---|---|
内毒素 | <1.0 EU per µg as determined by LAL test. |
保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months |
产品介绍
Intelectin-1 (ITLN1) is a secreted Protein and contains 1 fibrinogen C-terminal domain. Intelectin-1 is a 40 kDa Ca-dependent galactofuranose-binding lectin that is not a C-type lectin. It is expressed on multiple cell types and appears to participate in insulin signaling and microbe recognition. The Protein has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. It increases AKT phosphorylation in the absence and presence of insulin and it may play a role in the defense systemagainst microorganisms. It also may specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosy l residues, in a calcium-dependent manner.