货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
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KR0211 | NT3/ NGF-2, Human, Recombinant | 10ug |
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分子量 | 13.6 kDa |
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表观分子量 | 14 kDa |
片段与标签 | Tyr139-Thr257 |
生物活性 | Measured by its ability to bind Human NTRK2 in functional ELISA. The ED50 for this effect is less than 10 ug/ ml. |
物种 | Human |
表达宿主 | E.coli |
产品特性
纯度 | >95% as determined by reducing SDS-PAGE. |
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内毒素 | <1.0 EU per µg as determined by LAL test. |
保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks.<br/ >Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.<br/ >Aliquots of reconstituted samples are stable at < -20℃ for 3 months |
产品介绍
Neurotrophin-3 (NT-3) is a member of the NGF family of neurotrophic factors and is structurally related to β-NGF, BDNF and NT-4. The NT3 cDNA encodes a 257 amino acid residue precursor Protein with a signal peptide and a pro Protein that are cleaved to yield the 119 amino acid residue mature NT3.The amino acid sequences of mature human, murine and rat NT-3 are identical. NT-3 selectively promotes the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous systems.