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IL-33 (N-6His), Human, Recombinant

  • 货号:KR0193
货号 产品名称 规格 库存 价格 数量 购买
KR0193 IL-33 (N-6His), Human, Recombinant 10ug

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分子量 20.3 kDa
表观分子量 21 kDa
片段与标签 Ser112-Thr270 N-6His
生物活性 Testing in progress
物种 Human
表达宿主 E.coli

 

产品特性

 

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 <1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months

 

产品介绍

Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated Cytokines. IL-33 is a Cytokine that mediates its biological effects by binding to and signals through IL1RL1/ ST2 and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 Cytokines from polarized Th2 cells.

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