货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
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KR0193 | IL-33 (N-6His), Human, Recombinant | 10ug |
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分子量 | 20.3 kDa |
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表观分子量 | 21 kDa |
片段与标签 | Ser112-Thr270 N-6His |
生物活性 | Testing in progress |
物种 | Human |
表达宿主 | E.coli |
产品特性
纯度 | >95% as determined by reducing SDS-PAGE. |
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内毒素 | <1.0 EU per µg as determined by LAL test. |
保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months |
产品介绍
Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated Cytokines. IL-33 is a Cytokine that mediates its biological effects by binding to and signals through IL1RL1/ ST2 and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 Cytokines from polarized Th2 cells.