货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
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KR0182 | IL-18BP (C-Fc), Human, Recombinant | 10ug |
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分子量 | 44.7 kDa |
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表观分子量 | 55 kDa |
片段与标签 | Thr31-Gly194 C-Fc |
生物活性 | Testing in progress |
物种 | Human |
表达宿主 | Human Cells |
产品特性
纯度 | >95% as determined by reducing SDS-PAGE. |
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内毒素 | <1.0 EU per µg as determined by LAL test. |
保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months |
产品介绍
Interleukin-18-binding Protein, also known as Tadekinig-alfa and IL18BP, contains 1 Ig-like C2-type domain. IL18BP is constitutively expressed and secreted in mononuclear cells. IL18BP functions as an IL18 inhibitor. IL18BP binds to IL18, prevents the binding of IL18 to its Receptor, and thus inhibits IL18-induced IFN-gamma production. It has been shown that IL18BP may be a promising molecular approach to inhibit neointimal hyperplasia and arteriosclerosis progression following coronary and peripheral angioplasty.