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IL-18BP (C-Fc), Human, Recombinant

  • 货号:KR0182
货号 产品名称 规格 库存 价格 数量 购买
KR0182 IL-18BP (C-Fc), Human, Recombinant 10ug

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分子量 44.7 kDa
表观分子量 55 kDa
片段与标签 Thr31-Gly194 C-Fc
生物活性 Testing in progress
物种 Human
表达宿主 Human Cells

 

产品特性

 

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 <1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months

 

产品介绍

Interleukin-18-binding Protein, also known as Tadekinig-alfa and IL18BP, contains 1 Ig-like C2-type domain. IL18BP is constitutively expressed and secreted in mononuclear cells. IL18BP functions as an IL18 inhibitor. IL18BP binds to IL18, prevents the binding of IL18 to its Receptor, and thus inhibits IL18-induced IFN-gamma production. It has been shown that IL18BP may be a promising molecular approach to inhibit neointimal hyperplasia and arteriosclerosis progression following coronary and peripheral angioplasty.

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