货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
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KR0175 | IL-13 (C-6His), Human, Recombinant | 10ug |
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分子量 | 14.3 kDa |
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表观分子量 | 13 kDa |
片段与标签 | Leu25-Asn146 C-6His |
生物活性 | Measured in a cell proliferation assay using TF‑1 human erythroleukemic cellsThe ED50 for this effect is less than 5 ng/ ml. |
物种 | Human |
表达宿主 | Human Cells |
产品特性
纯度 | >95% as determined by reducing SDS-PAGE. |
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内毒素 | <1.0 EU per µg as determined by LAL test. |
保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months |
产品介绍
Interleukin-13 is also known as IL-13. It is a Protein that in humans is encoded by the IL13 gene. Interleukin-13 is an immunoregulatory Cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This Cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory Cytokines and Chemokines. This Cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils.