货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
---|---|---|---|---|---|---|
KR0173 | IL-12B/ IL-12 p40, Human, Recombinant | 10ug |
+
-
|
|
分子量 | 34.6 kDa |
---|---|
表观分子量 | 40-47 kDa |
片段与标签 | Ile23-Ser328 |
生物活性 | Testing in progress |
物种 | Human |
表达宿主 | Human Cells |
产品特性
纯度 | >95% as determined by reducing SDS-PAGE. |
---|---|
内毒素 | <1.0 EU per µg as determined by LAL test. |
保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months |
产品介绍
Interleukin-12 subunit beta (IL-12B) belongs to the type I Cytokine Receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-12B is a Cytokine that acts on T and natural killer cells, and has a broad array of biological activities. IL-12 is a disulfide-linked heterodimer composed of the 40 kD Cytokine Receptor encoded by IL12B and a 35 kD subunit encoded by IL12A. IL12 is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. It has been found to be important for sustaining a sufficient number of memory/ effector Th1 cells to mediate long-term protection to an intracellular pathogen.