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IL-10RB/ IL-10R2, Human, Recombinant

  • 货号:KR0169
货号 产品名称 规格 库存 价格 数量 购买
KR0169 IL-10RB/ IL-10R2, Human, Recombinant 10ug

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分子量 24.5 kDa
表观分子量 48 kDa
片段与标签 Met20-Ser220 C-6His
生物活性 Testing in progress
物种 Human
表达宿主 Human Cells

 

产品特性

 

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 <1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months

 

产品介绍

IL10RB is a single- pass type I membrane Protein and contains two fibronectin type-III domains. It is an accessory chain which is essential for the active Interleukin 10 Receptor complex. Coexpression of IL10RB and IL10RA Proteins has been shown to be required for IL10-induced signal transduction. Defects in IL10RB are the cause of inflammatory bowel disease type 25 (IBD25) which is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology.

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