货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
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KR0131 | FGF-12/ FHF-1, Human, Recombinant | 10ug |
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分子量 | 20.5 kDa |
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表观分子量 | 19 kDa |
片段与标签 | Met1-Thr181 |
生物活性 | Measured by its ability to bind Human FGF R3 in functional ELISA. The ED50 for this effect is less than 20 ug/ ml. |
物种 | Human |
表达宿主 | E.coli |
产品特性
纯度 | >95% as determined by reducing SDS-PAGE. |
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内毒素 | <1.0 EU per µg as determined by LAL test. |
保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months |
产品介绍
Fibroblast Growth Factor 12 (FGF-12) is a member of the fibroblast Growth Factor (FGF) family. FGF-12 is probably involved in nervous system development and function. FGF-12 lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfectedinto mammalian cells, this Protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.