货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
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KR0129 | CXCL5/ ENA-78, Human, Recombinant | 10ug |
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分子量 | 8.0 kDa |
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表观分子量 | 12 kDa |
片段与标签 | Leu44-Asn114 |
生物活性 | Measured by its ability to activate chimeric Receptor and induce reporter gene expression in HEK293 cell line used Splite TEV activity detection platform.The ED50 for this effect is less than 15 ng/ mL. |
物种 | Human |
表达宿主 | E.coli |
产品特性
纯度 | >95% as determined by reducing SDS-PAGE. |
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内毒素 | <1.0 EU per µg as determined by LAL test. |
保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks |
产品介绍
C-X-C Motif Chemokine 5 (CXCL5) is a member of the Intercrine Alpha (Chemokine CXC) family. CXCL5 can be cleaved into the following two chains, ENA-78 (8-78) and ENA-78 (9-78). In vitro, ENA-78 (8-78) and ENA-78 (9-78) show a threefold higher chemotactic activity for neutrophil granulocytes. CXCL5 is a secreted Protein and exercises the functions primarily through interactions with CXCR2. The upregulation of CXCL5 contributes to increased vascularization, tumor grown, and metastasis in many cancers.