货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
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KR0121 | GRO-α/ CXCL1 (C-6His), Human, Recombinant | 10ug |
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分子量 | 8.9 kDa |
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表观分子量 | 14 kDa |
片段与标签 | Ala35-Asn107 C-6His |
生物活性 | Testing in progress |
物种 | Human |
表达宿主 | Human Cells |
产品特性
纯度 | >95% as determined by reducing SDS-PAGE. |
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内毒素 | <1.0 EU per µg as determined by LAL test. |
保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months |
产品介绍
Chemokine (C-X-C Motif) Ligand 1 Protein (CXCL1) is a Growth Factor for melanoma cells and a chemotaxin for neutrophils and a member of the CXC Chemokine family that is a potent neutrophil attractant and activator and is also active toward basophils. CXCL1 is expressed by macrophages, neutrophils and epithelial cells; it has neutrophil chemoattractant activity. CXCL1 plays a critical nonredundant role in the development of experimental Lyme arthritis and carditis via CXCR2-mediated recruitment of neutrophils into the site of infection and may also have important pro-nociceptive effects via its direct actions on sensory neurons, and may induce long-term changes that involve Protein synthesis.