| 货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
|---|---|---|---|---|---|---|
| KR0119 | CNTF, Human, Recombinant | 10ug |
+
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| 分子量 | 22.93 kDa |
|---|---|
| 表观分子量 | 25 kDa |
| 片段与标签 | Ala2-Met200 |
| 物种 | Human |
| 表达宿主 | E.coli |
产品特性
| 纯度 | ＞95% as determined by reducing SDS-PAGE. |
|---|---|
| 内毒素 | ＜1.0 EU per µg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at ＜ -20°C, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at ＜ -20°C for 3 months. |
产品介绍
Ciliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes. CNTF has also been shown to prevent the degeneration of motor axons after axotomy. CNTF is highly conserved across species and exhibits cross-species activities. Human and rat CNTF share approximately 83% homology in their Protein sequence. CNTF is structurally related to IL6, IL11, LIF and OSM. All of these four helix bundle Cytokines share gp130 as a signal transducing subunit in their Receptor complexes. CNTF, like FGF acidic, FGF basic, and PD-ECGF (platelet-Derived endothelial cell Growth Factor), does not possess a signal sequence that would allow secretion of the factor by classical secretion pathways. The mechanism underlying the release of CNTF is unknown.
