| 货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
|---|---|---|---|---|---|---|
| KR0118 | CD30/ TNFRSF8 (C-Fc), Human, Recombinant | 10ug |
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| 分子量 | 65.2 kDa |
|---|---|
| 表观分子量 | 90-120 kDa |
| 片段与标签 | Phe19-Lys379 C-Fc |
| 生物活性 | Testing in progress |
| 物种 | Human |
| 表达宿主 | Human Cells |
产品特性
| 纯度 | ＞95% as determined by reducing SDS-PAGE. |
|---|---|
| 内毒素 | ＜1.0 EU per µg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at ＜ -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months |
产品介绍
CD30, also known as TNFRSF8, is a cell membrane Protein of the tumor necrosis factor Receptor family, which regulates proliferation/ apoptosis and antibody responses. CD30 is expressed by activated, but not by resting, T and B cells. Aberrant expression of CD30 by mastocytosis mast cells and interaction with its Ligand CD30L (CD153) appears to play an important role in the pathogenesis and clinical presentation of systemic mastocytosis. CD30 has been considered as a specific diagnostic biomarker of anaplastic large cell lymphoma (ALCL) and classical Hodgkin lymphoma (cHL). CD30 is also a biomarker used for targeted therapy by an antibody–drug conjugate.
