货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
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KR0115 | MEC/ CCL28, Human, Recombinant | 10ug |
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分子量 | 12.49 kDa |
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表观分子量 | 15 kDa |
片段与标签 | Ile20-Tyr127 |
物种 | Human |
表达宿主 | E.coli |
产品特性
纯度 | >95% as determined by reducing SDS-PAGE. |
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内毒素 | <1.0 EU per µg as determined by LAL test. |
保存 | Lyophilized Protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
产品介绍
Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel Chemokine that shares the most homology with CCL27/ CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. CCR10 (GPR2 orphan Receptor) is also the Receptor for CCL27/ CTACK. CCL28 is preferentially expressed by epithelial cells of diverse tissues, with highest expression level in normal and pathological colon. It is also expressed in normal and asthmatic lung tissues. Human and mouse CCL28 shares 83% sequence identity in their mature regions.