货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
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KR0112 | TARC/ CCL17 (C-6His), Human, Recombinant | 10ug |
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分子量 | 9.1 kDa |
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表观分子量 | 13 kDa |
片段与标签 | Ala24Ser94 |
物种 | Human |
表达宿主 | Human Cells |
产品特性
纯度 | >95% as determined by reducing SDS-PAGE. |
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内毒素 | <1.0 EU per µg as determined by LAL test. |
保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months |
产品介绍
C-C Motif Chemokine 17 (CCL17) is a novel CC Chemokine, it belongs to the intercrine beta (Chemokine CC) family. CCL17 is expressed at high levels in thymus, and at a lower level in lung, colon, and small intestine. CCL17 is also transiently expressed in stimulated peripheral blood mononuclear cells. Among CC Chemokine family members, CCL17 has approximately 24 - 29% amino acid sequence identity with RANTES, MIP-1 alpha, MIP-1 beta, MCP-1, MCP-2 and MCP-3. CCL17 has been identified to be Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. CCL17 plays a role in T-cell development in thymus and in trafficking and activation of mature T-cells.