| 货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
|---|---|---|---|---|---|---|
| KR0102 | TGFβ1/ TGFB1, Mouse, Recombinant | 10ug |
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| 分子量 | 12.8 kDa |
|---|---|
| 表观分子量 | 14 kDa |
| 片段与标签 | Ala279-Ser390 |
| 生物活性 | Measured by its ability to inhibit IL-4-dependent proliferation of TF‑1 human erythroleukemic cells.The ED50 for this effect is less than 1 ng/ ml. |
| 物种 | Mouse |
| 表达宿主 | Human Cells |
产品特性
| 纯度 | ＞95% as determined by reducing SDS-PAGE. |
|---|---|
| 内毒素 | ＜1.0 EU per μg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at ＜ -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months |
产品介绍
Transforming Growth Factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide Growth Factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric Receptor complex, consisting of a Ligand binding TGF-β Receptor type II (TβR-II), and a TGF-β Receptor type I (TβR-I). Signal transduction from the Receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.
