| 货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
|---|---|---|---|---|---|---|
| KR0075 | β-NGF/ NGF/ NGFB (Met130-Arg239), Mouse, Recombinant | 10ug |
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| 分子量 | 12.4 kDa |
|---|---|
| 表观分子量 | 12 kDa |
| 片段与标签 | Met130-Arg239 |
| 生物活性 | Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells.The ED50 for this effect is less than 5 ng/ ml. |
| 物种 | Mouse |
| 表达宿主 | E.coli |
产品特性
| 纯度 | ＞95% as determined by reducing SDS-PAGE. |
|---|---|
| 内毒素 | ＜1.0 EU per μg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks |
产品介绍
NGF is the first member discovered in the Neurotrophin family, which includes brain-Derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). These Proteins belong to the cysteine-knot family of Growth Factors that assume stable dimeric structures. Mouse beta -NGF is a homodimer of two 120 amino acid polypeptides. It shares approximately 90% homology at the amino acid level with human beta -NGF and 95.8% with rat beta -NGF. NGF signaling has been shown to play an important role in neuroprotection and repair. β-NGF acts as a growth and differentiation factor for B lymphocytes, and enhances B-cell survival. It is a potent neurotrophic factor that signals through its Receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems.
