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RANK/ TNFRSF11A/ CD265 (C-6His), Human, Recombinant

  • 货号:KR0061
货号 产品名称 规格 库存 价格 数量 购买
KR0061 RANK/ TNFRSF11A/ CD265 (C-6His), Human, Recombinant 10ug

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分子量 21.1 kDa
表观分子量 25-30 kDa
片段与标签 Ile30-Pro212 C-6His
生物活性 Testing in progress
物种 Human
表达宿主 Human Cells

 

产品特性

 

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 <1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months

 

产品介绍

Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor Receptor (TNFR) molecular superfamily. RANK is the Receptor for RANK-Ligand (RANKL) and part of the RANK/ RANKL/ OPG signaling pathway that regulates osteoclast differentiation and activation. It plays a vital role in bone remodeling and repair, immune cell function, lymph node development, thermal regulation, and mammary gland development. RANK is constitutively expressed in skeletal muscle, thymus, liver, colon, small intestine, adrenal gland, osteoclast, mammary gland epithelial cells, prostate, vascular cell, and pancreas.

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