货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
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KR0059 | TNF-α/ TNFA/ TNFSF2, Rabbit, Recombinant | 10ug |
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分子量 | 17.59 kDa |
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表观分子量 | 18 kDa |
片段与标签 | Val77-Leu235 |
生物活性 | Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is less than 20 pg/ ml. |
物种 | Rabbit |
表达宿主 | E.coli |
产品特性
纯度 | >95% as determined by reducing SDS-PAGE. |
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内毒素 | <1.0 EU per µg as determined by LAL test. |
保存 | Lyophilized Protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
产品介绍
Tumor necrosis factor alpha (TNFα) is the prototypic Ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of Receptors TNF-R1 (TNF Receptor type 1,p55R) and TNF-R2 (TNF Receptor type 2,p75R). TNFα is a pleiotropic Cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNFα is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.