货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
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KR0058 | TNF-α/ TNFA/ TNFSF2, Mouse, Recombinant | 10ug |
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分子量 | 16.4 kDa |
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表观分子量 | 14 kDa |
片段与标签 | Asp89-Leu235 |
生物活性 | Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is less than 0.08 ng/ ml. |
物种 | Mouse |
表达宿主 | E.coli |
产品特性
纯度 | >95% as determined by reducing SDS-PAGE. |
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内毒素 | <1.0 EU per μg as determined by LAL test. |
保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months |
产品介绍
Tumor Necrosis Factor (TNF) is a member of the Tumor Necrosis Factor family. TNF exists as a homotrimer and interacts with SPPL2B. TNF is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. TNF is a key Cytokine in the development of several inflammatory disorders. It contributes to the development of type 2 diabetes throught its effects on insulin resistance and fatty acid metabolism.