货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
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KR0048 | IL-1α/ IL1F1, Human, Recombinant | 10ug |
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分子量 | 18 kDa |
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表观分子量 | 17 kDa |
片段与标签 | Ser113-Ala271 |
生物活性 | Measured by its ability to induce NFKB reporter gene expression in HEK 293 cell line.The ED50 for this effect is less than 50 pg/ mL. |
物种 | Human |
表达宿主 | E.coli |
产品特性
纯度 | >95% as determined by reducing SDS-PAGE. |
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内毒素 | <1.0 EU per µg as determined by LAL test. |
保存 | Lyophilized Protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
产品介绍
Interleukin-1 alpha (IL1α) is a Cytokine member of the Interleukin-1 family. IL-1 consists of two distinct forms: IL1α and IL1β that recognize the same cell surface Receptors but are distinct Proteins with approximately 25% amino acid sequence identity. IL1α is constitutively produced by epithelial cells and plays an essential role in maintenance of skin barrier function. Upon stimulation, a wide variety of cells including osteoblasts, monocytes, macrophages can be induced to express IL1α. IL1α possesses a wide range of metabolic, physiological, haematopoietic activities, and is critically involved in the regulation of the immune responses and inflammatory responses.