货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
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KR0046 | M-CSF/ CSF1, Mouse, Recombinant | 10ug |
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分子量 | 26.0 kDa |
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表观分子量 | 43 kDa |
片段与标签 | Lys33-Glu262 |
生物活性 | Measured in a cell proliferation assay using M‑NFS‑60 mouse myelogenous leukemia lymphoblast cellsThe ED50 for this effect is less than 10 ng/ ml. |
物种 | Mouse |
表达宿主 | Human Cells |
产品特性
纯度 | >95% as determined by reducing SDS-PAGE. |
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内毒素 | <1.0 EU per μg as determined by LAL test. |
保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months |
产品介绍
Macrophage colony-stimulating factor 1 (M-csf)is a single-pass type I membrane Protein . It is a hematopoietic Growth Factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/ macrophage cell lineage. By interacting with its membrane Receptor, M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.