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M-CSF/ CSF1 (C-6His), Human, Recombinant

  • 货号:KR0045
货号 产品名称 规格 库存 价格 数量 购买
KR0045 M-CSF/ CSF1 (C-6His), Human, Recombinant 10ug

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分子量 26.2 kDa
表观分子量 41 kDa
片段与标签 Glu33-Arg255 C-6His
生物活性 Measured by its ability to acclerate M-NFS-60-dependent proliferation.The ED50 for this effect is less than 10 ng/ ml
物种 Human
表达宿主 Human Cells

 

产品特性

 

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 <1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months

 

产品介绍

Macrophage Colony-Stimulating Factors (m-csf) are Cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and themonocytes-macrophages. CSF-1 promotes the release of proinflammatory Chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. CSF-1 is required for normal male and female fertility and promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. it also plays a role in lipo Protein clearance.

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