货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
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KR0045 | M-CSF/ CSF1 (C-6His), Human, Recombinant | 10ug |
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分子量 | 26.2 kDa |
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表观分子量 | 41 kDa |
片段与标签 | Glu33-Arg255 C-6His |
生物活性 | Measured by its ability to acclerate M-NFS-60-dependent proliferation.The ED50 for this effect is less than 10 ng/ ml |
物种 | Human |
表达宿主 | Human Cells |
产品特性
纯度 | >95% as determined by reducing SDS-PAGE. |
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内毒素 | <1.0 EU per µg as determined by LAL test. |
保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months |
产品介绍
Macrophage Colony-Stimulating Factors (m-csf) are Cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and themonocytes-macrophages. CSF-1 promotes the release of proinflammatory Chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. CSF-1 is required for normal male and female fertility and promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. it also plays a role in lipo Protein clearance.