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GM-CSF/ CSF2 (E.coli), Human, Recombinant

  • 货号:KR0038
货号 产品名称 规格 库存 价格 数量 购买
KR0038 GM-CSF/ CSF2 (E.coli), Human, Recombinant 10ug

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分子量 14.6 kDa
表观分子量 14 kDa
片段与标签 Ala18-Glu144
生物活性 Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is less than 0.2 ng/ mL.
物种 Human
表达宿主 E.coli

 

产品特性

 

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 <1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.

 

产品介绍

Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a Growth Factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to Cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a Growth Factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic, monocytes/ macrophages and eosinophils. GM-CSF has a functional role on non-hematopoitic cells. It can induce human endothelial cells to migrate and proliferate. Additionally, GM-CSF can also stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma and adenocarcinoma cell lines.

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