货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
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KR0001 | IL-2 (C-6His), Rat, Recombinant | 10ug |
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分子量 | 16.3 kDa |
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表观分子量 | 16 kDa |
片段与标签 | Ala21-Gln155 |
物种 | Rat |
表达宿主 | Human Cells |
产品特性
纯度 | >95% as determined by reducing SDS-PAGE. |
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内毒素 | <1.0 EU per µg as determined by LAL test. |
保存 | Store at < -20℃, stable for 6 monthshs after receipt.<br/ >Please minimize freeze-thaw cycles |
产品介绍
Interleukin-2 (IL-2)is a O-glycosylated four α-helix bundle Cytokine that has potent stimulatory activity for antigenactivated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. Mature rat IL-2 shares 66% and 73% amino acid sequence identity with human and mouse IL-2,respectively. The Receptor for IL-2 consists of three subunits that are present on the cell surface in varying preformed complexes. IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/ IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.